Monday, September 5, 2016

memantine


me-MAN-teen


Commonly used brand name(s)

In the U.S.


  • Namenda

  • Namenda XR

Available Dosage Forms:


  • Capsule, Extended Release

  • Tablet

  • Solution

Therapeutic Class: Central Nervous System Agent


Pharmacologic Class: N-Methyl-D-Aspartate Receptor Antagonist


Uses For memantine


Memantine is used to treat moderate to severe Alzheimer's disease. Memantine is not a cure for Alzheimer's disease but it can help people with the disease. Memantine will not cure Alzheimer's disease, and it will not stop the disease from getting worse.


memantine is available only with your doctor's prescription.


Before Using memantine


In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For memantine, the following should be considered:


Allergies


Tell your doctor if you have ever had any unusual or allergic reaction to memantine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.


Pediatric


Appropriate studies on the relationship of age to the effects of memantine have not been performed in the pediatric population.


Geriatric


No information is available on the relationship of age to the effects of memantine in geriatric patients.


Pregnancy








Pregnancy CategoryExplanation
All TrimestersBAnimal studies have revealed no evidence of harm to the fetus, however, there are no adequate studies in pregnant women OR animal studies have shown an adverse effect, but adequate studies in pregnant women have failed to demonstrate a risk to the fetus.

Breast Feeding


There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.


Interactions with Medicines


Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.


Interactions with Food/Tobacco/Alcohol


Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.


Other Medical Problems


The presence of other medical problems may affect the use of memantine. Make sure you tell your doctor if you have any other medical problems, especially:


  • Epilepsy or seizures or

  • Urinary tract problems (e.g., bladder problems, difficulty with urination)—Use with caution. May make these conditions worse.

  • Kidney disease or

  • Liver disease—Use with caution. The effects may be increased because of slower removal of the medicine from the body.

Proper Use of memantine


Take memantine exactly as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered.


memantine comes with a patient information insert. Read and follow the instructions in the insert carefully. Ask your doctor if you have any questions.


You may take memantine with or without food.


Swallow the extended-release capsules whole. Do not break, crush, or chew them.


If you cannot swallow the extended-release capsule, you may open it and pour the medicine into a small amount of soft food such as applesauce. Stir this mixture well and swallow it without chewing.


For patients taking the oral liquid:


  • Remove the oral dosing syringe along with the cap and plastic tube from the bag and attach to tube to the cap.

  • Open the child-resistant cap on the bottle by pushing down on the cap while turning the cap counter-clockwise (to the left) and remove the cap and seal from the bottle.

  • Insert the plastic tube fully into the bottle and screw the cap tightly onto the bottle by turning the cap clockwise (to the right).

  • Keeping the bottle upright on the table, remove the lid to uncover the opening on the top of the cap. With the plunger fully depressed, insert the tip of the syringe firmly into the opening of the cap.

  • While holding the syringe, gently pull the plunger of the syringe up to draw medicine into the syringe.

  • Remove the syringe from the cap opening. Invert the syringe (point tip upwards) and slowly press the plunger to a level that pushed out any large air bubbles that may be present. Keep the plunger in this position.

  • Re-insert the tip of the syringe into the cap opening. While holding the syringe, continue to gently pull out the plunger until the bottom of the black ring of the plunger reaches the appropriate mark on the syringe that corresponds to the dose prescribed.

  • Remove the syringe from the bottle and swallow the oral solution directly from the syringe. Do not mix with any other liquid.

  • After use, reseal the bottle by snapping the attached lid closed.

  • Rinse the empty syringe by inserting the open end of the syringe into a glass of water, pulling the plunger out to draw in water, and pushing the plunger in to remove the water. Repeat several times. Allow the syringe to air dry.

Dosing


The dose of memantine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of memantine. If your dose is different, do not change it unless your doctor tells you to do so.


The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.


  • For treatment of Alzheimer's disease:
    • For oral dosage form (extended-release capsules):
      • Adults—At first, 7 milligrams (mg) once a day. Your doctor may gradually increase your dose as needed. However, the dose is usually not more than 28 mg per day.

      • Children—Use and dose must be determined by your doctor.


    • For oral dosage form (solution and tablets):
      • Adults—At first, 5 milligrams (mg) once a day. Your doctor may gradually increase your dose as needed. However, the dose is usually not more than 10 mg two times a day.

      • Children—Use and dose must be determined by your doctor.



Missed Dose


If you miss a dose of memantine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.


Storage


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.


Keep out of the reach of children.


Do not keep outdated medicine or medicine no longer needed.


Ask your healthcare professional how you should dispose of any medicine you do not use.


Precautions While Using memantine


It is very important that your doctor check your progress at regular visits to make sure that memantine is working properly and to check for unwanted effects.


Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.


memantine Side Effects


Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.


Check with your doctor immediately if any of the following side effects occur:


Less common
  • Bloating or swelling of the face, arms, hands, lower legs, or feet

  • blurred vision

  • dizziness

  • headache

  • nervousness

  • pounding in the ears

  • rapid weight gain

  • slow or fast heartbeat

  • tingling of the hands or feet

  • unusual weight gain or loss

Incidence not known
  • Abdominal or stomach pain

  • agitation

  • black, tarry stools

  • bleeding gums

  • blistering, peeling, or loosening of the skin

  • blood in the urine or stools

  • chest pain

  • coma

  • constipation

  • continuing vomiting

  • convulsions

  • dark-colored urine

  • decreased urine output

  • depression

  • fainting

  • fast, pounding, or irregular heartbeat or pulse

  • general feeling of tiredness or weakness

  • high fever

  • high or low blood pressure

  • hostility

  • increased sweating

  • indigestion

  • infection from breathing foreign substances into the lungs

  • itching

  • lethargy

  • light-colored stools

  • lip smacking or puckering

  • loss of consciousness

  • muscle twitching

  • no blood pressure

  • no breathing

  • no pulse

  • numbness or tingling in the face, arms, or legs

  • pain in the stomach, side, or abdomen, possibly radiating to the back

  • pain or swelling in the arms or legs without any injury

  • pain, tension, and weakness upon walking that subsides during periods of rest

  • pinpoint red spots on the skin

  • pounding, slow heartbeat

  • puffing of the cheeks

  • rapid or worm-like movements of the tongue

  • rapid weight gain

  • recurrent fainting

  • red irritated eyes

  • red skin lesions, often with a purple center

  • seizures

  • severe constipation

  • severe headache

  • severe muscle stiffness

  • severe vomiting

  • sores, ulcers, or white spots in the mouth or on the lips

  • stupor

  • sudden severe weakness

  • swelling of the face, ankles, or hands

  • total body jerking

  • trouble with speaking or walking

  • troubled breathing

  • twitching, twisting, or uncontrolled repetitive movements of the tongue, lips, face, arms, or legs

  • uncontrolled chewing movements

  • unusual bleeding or bruising

  • unusually pale skin

  • vomiting

  • yellow eyes and skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:


More common
  • Confusion

Less common
  • Anxiety

  • back pain

  • bladder pain

  • bloody or cloudy urine

  • change in walking and balance

  • chills

  • clumsiness or unsteadiness

  • cough producing mucus

  • coughing

  • diarrhea

  • difficult, burning, or painful urination

  • difficulty with breathing

  • difficulty with moving

  • discouragement

  • dry mouth

  • fear

  • feeling sad or empty

  • fever

  • frequent urge to urinate

  • general feeling of discomfort or illness

  • hyperventilation

  • insomnia

  • irritability

  • joint pain

  • loss of appetite

  • loss of bladder control

  • loss of interest or pleasure

  • lower back or side pain

  • muscle pain or stiffness

  • nausea

  • nervousness

  • pain

  • pain in the joints

  • restlessness

  • seeing, hearing, or feeling things that are not there

  • shortness of breath

  • sleepiness or unusual drowsiness

  • sore throat

  • tightness in the chest

  • tiredness

  • trouble with concentrating

  • trouble with sleeping

  • unusual tiredness or weakness

  • vomiting

  • wheezing

Incidence not known
  • Burning feeling in the chest or stomach

  • burning, numbness, pain, or tingling in all fingers except smallest finger

  • cold sweats

  • cool pale skin

  • decreased interest in sexual intercourse

  • difficulty with swallowing

  • general feeling of discomfort or illness

  • heartburn

  • inability to have or keep an erection

  • increased hunger

  • large amounts of fat in the blood

  • loss in sexual ability, desire, drive, or performance

  • nightmares

  • shakiness

  • slurred speech

  • stomach cramps

  • stomach upset

  • tenderness in the stomach area

  • watery or bloody diarrhea

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.


Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: memantine side effects (in more detail)



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More memantine resources


  • Memantine Side Effects (in more detail)
  • Memantine Use in Pregnancy & Breastfeeding
  • Memantine Drug Interactions
  • Memantine Support Group
  • 10 Reviews for Memantine - Add your own review/rating


  • Memantine MedFacts Consumer Leaflet (Wolters Kluwer)

  • Memantine Hydrochloride Monograph (AHFS DI)

  • Namenda Prescribing Information (FDA)

  • Namenda Consumer Overview



Compare memantine with other medications


  • Alzheimer's Disease

Melphalan


Pronunciation: MEL-fa-lan
Generic Name: Melphalan
Brand Name: Alkeran

Melphalan should only be used under the supervision of a doctor experienced with the use of cancer medicines. Melphalan may cause a decrease in the body's blood cells (bone marrow suppression), which could cause bleeding problems or infection. It may also cause a certain type of blood cell cancer (leukemia) or a severe allergic reaction. Notify your doctor immediately if you develop unusual bleeding or bruising, unusual fatigue, symptoms of an allergic reaction (eg, rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue), or signs of an infection (eg, fever, chills, persistent sore throat).





Melphalan is used for:

Treating symptoms of a certain type of cancer (multiple myeloma). It may also be used for other conditions as determined by your doctor.


Melphalan is an alkylating agent. It works by destroying resting and rapidly dividing tumor cells in certain types of cancer.


Do NOT use Melphalan if:


  • you are allergic to any ingredient in Melphalan

  • you have used Melphalan before and it did not work

  • you have taken or will be taking palifermin within 24 hours before or after using Melphalan

  • you are taking nalidixic acid

Contact your doctor or health care provider right away if any of these apply to you.



Before using Melphalan:


Some medical conditions may interact with Melphalan. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:


  • if you are pregnant, planning to become pregnant, or are breast-feeding

  • if you are a female of childbearing age

  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

  • if you have allergies to medicines, foods, or other substances

  • if you have bone marrow problems, low white blood cell count, low platelet count, an infection, kidney problems, shingles, or chickenpox

  • if you have had chemotherapy or radiation treatment

  • if you have recently had or are scheduled to have a vaccine

Some MEDICINES MAY INTERACT with Melphalan. Tell your health care provider if you are taking any other medicines, especially any of the following:


  • Cisplatin because the risk of Melphalan's side effects may be increased

  • Carmustine (BCNU), cyclosporine, or nalidixic acid because serious lung, kidney, or bowel problems may occur

  • Palifermin because if mouth or tongue sores develop, they may be more severe or last longer

This may not be a complete list of all interactions that may occur. Ask your health care provider if Melphalan may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.


How to use Melphalan:


Use Melphalan as directed by your doctor. Check the label on the medicine for exact dosing instructions.


  • Melphalan is usually given as an injection at your doctor's office, hospital, or clinic. If you will be using Melphalan at home, a health care provider will teach you how to use it. Be sure you understand how to use Melphalan. Follow the procedures you are taught when you use a dose. Contact your health care provider if you have any questions.

  • Do not use Melphalan if it contains particles, is cloudy or discolored, or if the vial is cracked or damaged.

  • If you spill Melphalan on your skin, wash it off right away with soap and water. Clean any areas (tables, counters) where Melphalan may have spilled or sprayed.

  • Keep this product, as well as syringes and needles, out of the reach of children and pets. Do not reuse needles, syringes, or other materials. Ask your health care provider how to dispose of these materials after use. Follow all local rules for disposal.

  • If you miss a dose of Melphalan, contact your doctor immediately.

Ask your health care provider any questions you may have about how to use Melphalan.



Important safety information:


  • Melphalan may lower the ability of your body to fight infection. Avoid contact with people who have colds or infections. Tell your doctor if you notice signs of infection like fever, sore throat, rash, or chills.

  • Do not receive a live vaccine (eg, measles, mumps) while you are taking Melphalan. Talk with your doctor before you receive any vaccine.

  • Melphalan may reduce the number of clot-forming cells (platelets) in your blood. Avoid activities that may cause bruising or injury. Tell your doctor if you have unusual bruising or bleeding. Tell your doctor if you have dark, tarry, or bloody stools.

  • If nausea, vomiting, or loss of appetite occurs, ask your doctor or pharmacist for ways to lessen these effects.

  • Use of Melphalan may increase your risk of developing another type of cancer. The risk may be greater if you use higher doses of Melphalan or if you use it for a longer period of time. Discuss any questions or concerns with your doctor.

  • Melphalan may affect the ovaries. This may cause irregular or absent menstrual periods and decreased fertility in some women. Discuss any questions or concerns with your doctor.

  • Melphalan may affect the testicles and cause decreased fertility in some men. This may be permanent in some patients. Discuss any questions or concerns with your doctor.

  • Lab tests, including complete blood cell counts, may be performed while you use Melphalan. These tests may be used to monitor your condition or to check for side effects. Be sure to keep all doctor and lab appointments.

  • Melphalan should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.

  • PREGNANCY and BREAST-FEEDING: Melphalan has been shown to cause harm to the fetus. Avoid becoming pregnant while taking Melphalan. If you think you may be pregnant, contact your doctor. You will need to discuss the benefits and risks of using Melphalan while you are pregnant. It is unknown if Melphalan is found in breast milk. Do not breast-feed while taking Melphalan.


Possible side effects of Melphalan:


All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:



Diarrhea; hair loss; nausea; vomiting.



Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); black, tarry stools; blood in urine or stools; chest pain; dark urine; dizziness or light-headedness; fainting; fast heartbeat; fatigue; fever or chills; irregular or absent menstrual periods; numbness of an arm or leg; pain, swelling, or redness at the injection site; pale stools; persistent cough; persistent loss of appetite; severe or persistent diarrhea, nausea, or vomiting; shortness of breath; sore throat; sores on the mouth, tongue, or lips; stomach pain; sudden, severe headache; swelling of the hands, ankles, or feet; unusual bruising or bleeding; unusual lumps or growths; unusual tiredness or weakness; weight loss; yellowing eyes and skin.



This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.


See also: Melphalan side effects (in more detail)


If OVERDOSE is suspected:


Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include decreased urination; diarrhea; paralysis; seizures; severe drowsiness; severe nausea and vomiting; sores on the mouth, tongue, or lips; symptoms of stomach or bowel bleeding (eg, black, tarry, or bloody stools; vomit that looks like coffee grounds); trouble breathing.


Proper storage of Melphalan:

Melphalan is usually handled and stored by a health care provider. If you are using Melphalan at home, store Melphalan as directed by your pharmacist or health care provider. Keep Melphalan out of the reach of children and away from pets.


General information:


  • If you have any questions about Melphalan, please talk with your doctor, pharmacist, or other health care provider.

  • Melphalan is to be used only by the patient for whom it is prescribed. Do not share it with other people.

  • If your symptoms do not improve or if they become worse, check with your doctor.

  • Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Melphalan. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.



Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Melphalan resources


  • Melphalan Side Effects (in more detail)
  • Melphalan Dosage
  • Melphalan Use in Pregnancy & Breastfeeding
  • Melphalan Drug Interactions
  • Melphalan Support Group
  • 0 Reviews for Melphalan - Add your own review/rating


  • Melphalan Prescribing Information (FDA)

  • Melphalan Monograph (AHFS DI)

  • Melphalan Professional Patient Advice (Wolters Kluwer)

  • melphalan Concise Consumer Information (Cerner Multum)

  • melphalan Advanced Consumer (Micromedex) - Includes Dosage Information

  • Alkeran Prescribing Information (FDA)



Compare Melphalan with other medications


  • Multiple Myeloma
  • Ovarian Cancer

Men's Rogaine Topical



Generic Name: minoxidil (Topical route)

min-OX-i-dil

Commonly used brand name(s)

In the U.S.


  • Men's Rogaine

  • Rogaine

  • Rogaine For Men Extra Strength

  • Women's Rogaine

In Canada


  • Apo-Gain

  • Gen-Minoxidol

  • Hairgro

  • Hair Regrowth Treatment

  • Med Minoxidil

  • Minox

Available Dosage Forms:


  • Solution

  • Foam

Therapeutic Class: Alopecia Agent


Uses For Men's Rogaine


Minoxidil applied to the scalp is used to stimulate hair growth in adult men and women with a certain type of baldness. The exact way that this medicine works is not known.


If hair growth is going to occur with the use of minoxidil, it usually occurs after the medicine has been used for several months and lasts only as long as the medicine continues to be used. Hair loss will begin again within a few months after minoxidil treatment is stopped.


In the U.S., this medicine is available without a prescription.


Before Using Men's Rogaine


In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:


Allergies


Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.


Pediatric


Appropriate studies have not been performed on the relationship of age to the effects of topical minoxidil in children. Safety and efficacy have not been established ..


Geriatric


Appropriate studies performed to date have not demonstrated geriatrics-specific problems that would limit the usefulness of topical minoxidil in the elderly. However, studies have shown that the medicine works best in younger patients who have a short history of hair loss. Minoxidil has not been studied in patients older than 65 years of age .


Pregnancy








Pregnancy CategoryExplanation
All TrimestersCAnimal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding


Studies in women suggest that this medication poses minimal risk to the infant when used during breastfeeding.


Interactions with Medicines


Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.


Interactions with Food/Tobacco/Alcohol


Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.


Other Medical Problems


The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:


  • Any other skin problems, an irritation, or a sunburn on the scalp—These conditions may cause too much topical minoxidil to be absorbed into the body and may increase the chance of side effects.

  • Heart disease or

  • Hypertension (high blood pressure)—Topical minoxidil has not been studied in patients who have these conditions, but more serious problems may develop for these patients if they use more medicine than is recommended over a large area and too much minoxidil is absorbed into the body.

Proper Use of minoxidil

This section provides information on the proper use of a number of products that contain minoxidil. It may not be specific to Men's Rogaine. Please read with care.


This medicine usually comes with patient instructions. It is important that you read the instructions carefully.


It is very important that you use this medicine only as directed. Do not use more of it and do not use it more often than your doctor ordered. To do so may increase the chance of it being absorbed through the skin. For the same reason, do not apply minoxidil to other parts of your body. Absorption into the body may affect the heart and blood vessels and cause unwanted effects.


Do not use any other skin products on the same skin area on which you use minoxidil. Hair coloring, hair permanents, and hair relaxers may be used during minoxidil therapy as long as the scalp is washed just before applying the hair coloring, permanent, or relaxer. Minoxidil should not be used 24 hours before and after the hair treatment procedure. Be sure to not double your doses of minoxidil to make up for any missed doses.


To apply minoxidil topical solution:


  • Make sure your hair and scalp are completely dry before applying this medicine.

  • Apply the amount prescribed to the area of the scalp being treated, beginning in the center of the area. Follow your doctor's instructions on how to apply the solution, using the applicator provided.

  • Do not shampoo your hair for 4 hours after applying minoxidil.

  • Immediately after using this medicine, wash your hands to remove any medicine that may be on them.

  • Do not use a hairdryer to dry the scalp after you apply minoxidil solution. Blowing with a hairdryer on the scalp may make the treatment less effective.

  • Allow the minoxidil to completely dry for 2 to 4 hours after applying it, including before going to bed. Minoxidil can stain clothing, hats, or bed linen if your hair or scalp is not fully dry after using the medicine.

  • Avoid transferring the medicine while wet to other parts of the body. This can occur if the medicine gets on your pillowcase or bed linens or if your hands are not washed after applying minoxidil.

To apply minoxidil topical foam:


  • Open the container by matching the arrow on can ring with the arrow on cap. Pull off the cap.

  • Part the hair into one or more rows to expose the hair thinning area on the scalp.

  • Hold the can upside down and press the nozzle to put foam on your fingers.

  • Use your fingers to spread the foam over the hair loss area and gently massage into your scalp.

  • Immediately after using this medicine, wash your hands to remove any medicine that may be on them .

If your scalp becomes abraded, irritated, or sunburned, check with your doctor before applying minoxidil.


Minoxidil topical foam or solution is for use on the scalp only. Keep this medicine away from the eyes, nose, and mouth. If you should accidentally get some in your eyes, nose, or mouth, flush the area thoroughly with cool tap water. If you are using the pump spray, be careful not to breathe in the spray .


Do not use the foam near heat or open flame, or while smoking. Do not puncture, break, or burn the aerosol can .


Dosing


The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.


The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.


  • For hair growth:
    • For topical solution dosage form:
      • Adults—Apply 1 milliliter (mL) to the scalp two times a day.

      • Children—Use and dose must be determined by the doctor.


    • For topical foam dosage form:
      • Adults—Apply half a capful to the scalp two times a day.

      • Children—Use and dose must be determined by your doctor .



Missed Dose


If you miss a dose of this medicine, apply it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule.


Storage


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.


Keep out of the reach of children.


Do not keep outdated medicine or medicine no longer needed.


Flammable: Keep away from fire or flame.


Precautions While Using Men's Rogaine


It is important that your doctor check your progress at regular visits to make sure that this medicine is working properly and to check for unwanted effects.


Tell your doctor if you notice continued itching, redness, or burning of your scalp after you apply minoxidil. If the itching, redness, or burning is severe, wash the medicine off and check with your doctor before using it again.


Hair loss may continue for 2 weeks after you start using minoxidil. Tell your doctor if your hair loss continues after 2 weeks. Also, tell your doctor if your hair growth does not increase after using minoxidil for 4 months.


Men's Rogaine Side Effects


Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.


Check with your doctor as soon as possible if any of the following side effects occur:


Less common
  • Itching or skin rash (continued)

Rare
  • Acne at site of application

  • burning of scalp

  • facial hair growth

  • increased hair loss

  • inflammation or soreness at root of hair

  • reddened skin

  • swelling of face

Signs and symptoms of too much medicine being absorbed into the body—Rare
  • Blurred vision or other changes in vision

  • chest pain

  • dizziness

  • fainting

  • fast or irregular heartbeat

  • flushing

  • headache

  • lightheadedness

  • numbness or tingling of hands, feet, or face

  • swelling of face, hands, feet, or lower legs

  • weight gain (rapid)

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.


Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.



The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.


The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.


More Men's Rogaine Topical resources


  • Men's Rogaine Topical Use in Pregnancy & Breastfeeding
  • Men's Rogaine Topical Drug Interactions
  • Men's Rogaine Topical Support Group
  • 7 Reviews for Men's Rogaine Topical - Add your own review/rating


Compare Men's Rogaine Topical with other medications


  • Alopecia

Menostar Transdermal


Generic Name: estradiol (Transdermal route)

es-tra-DYE-ol

Transdermal route(Emulsion)

Estrogens increase the risk of endometrial cancer; monitor for abnormal vaginal bleeding. Estrogens with or without progestins should not be used for the prevention of cardiovascular disease or dementia. Increased risks of myocardial infarction, stroke, invasive breast cancer, pulmonary emboli, and deep vein thrombosis in postmenopausal women (50 to 79 years of age) have been reported. An increased risk of developing probable dementia in postmenopausal women 65 years of age or older has also been reported. Risks should be assumed to be similar for other doses, combinations, and dosage forms of estrogens and progestins. Estrogens, with or without progestins, should be prescribed at the lowest effective doses and for the shortest duration possible .


Transdermal route(Patch, Extended Release)

Estrogens increase the risk of endometrial cancer; monitor for abnormal vaginal bleeding. Estrogens with or without progestins should not be used for the prevention of cardiovascular disease or dementia. Increased risks of myocardial infarction, stroke, invasive breast cancer, pulmonary emboli, and deep vein thrombosis in postmenopausal women (50 to 79 years of age) have been reported. An increased risk of developing probable dementia in postmenopausal women 65 years of age or older has also been reported. Risks should be assumed to be similar for other doses, combinations, and dosage forms of estrogens and progestins. Estrogens, with or without progestins, should be prescribed at the lowest effective doses and for the shortest duration possible.


Transdermal route(Gel/Jelly)

Estrogens increase the risk of endometrial cancer; monitor for abnormal vaginal bleeding. Estrogens with or without progestins should not be used for the prevention of cardiovascular disease. Increased risks of myocardial infarction, stroke, invasive breast cancer, pulmonary emboli, and deep vein thrombosis in postmenopausal women (50 to 79 years of age) have been reported. Risks should be assumed to be similar for other doses, combinations, and dosage forms of estrogens and progestins. Estrogens, with or without progestins, should be prescribed at the lowest effective doses and for the shortest duration possible .


Transdermal route(Spray)

Unopposed estrogens increase the risk of endometrial cancer. Adding a progestin will reduce the risk of endometrial hyperplasia, which may be a precursor to endometrial cancer. Diagnostic measures should be undertaken to rule out malignancy in postmenopausal women with undiagnosed persistent or recurring abnormal genital bleeding. Estrogens with or without progestins should not be used for the prevention of cardiovascular disease or dementia. Increased risks of stroke and deep vein thrombosis in postmenopausal women (50 to 79 years of age) using estrogen alone have been reported. Increased risks of myocardial infarction, stroke, invasive breast cancer, pulmonary emboli, and deep vein thrombosis in postmenopausal women (50 to 79 years of age) using estrogens combined with progestins have been reported. An increased risk of developing probable dementia in postmenopausal women 65 years of age or older has also been reported in women receiving estrogen alone or estrogen combined with progestins. Risks should be assumed to be similar for other doses, combinations, and dosage forms of estrogens and progestins. Estrogens, with or without progestins, should be prescribed at the lowest effective doses and for the shortest duration possible. Breast budding and breast masses in prepubertal females and gynecomastia and breast masses in prepubertal males have been reported following unintentional secondary exposure. Patients should strictly adhere to recommended instructions for use .



Commonly used brand name(s)

In the U.S.


  • Alora

  • Climara

  • Divigel

  • Elestrin

  • Esclim

  • Estraderm

  • Estrasorb

  • EstroGel

  • Evamist

  • Menostar

  • Vivelle

  • Vivelle-Dot

In Canada


  • Estradot Transdermal

  • Estradot Transdermal Therapeutic System

  • Estradot Transdermal Therapeutic System

  • Oesclim

  • Rhoxal-Estradiol Derm 50

  • Rhoxal-Estradiol Derm 75

  • Roxal-Estradiol Derm 100

  • Vivelle 100 Mcg

  • Vivelle 25 Mcg

  • Vivelle 37.5 Mcg

Available Dosage Forms:


  • Patch, Extended Release

  • Gel/Jelly

  • Spray

  • Emulsion

Therapeutic Class: Endocrine-Metabolic Agent


Pharmacologic Class: Estrogen


Uses For Menostar


Estradiol transdermal spray is used to treat moderate to severe hot flashes and other symptoms of menopause or low amounts of estrogen.


Estradiol is an estrogen hormone. The hormone from the spray is absorbed through your skin into your body. It works by preventing symptoms, such as feelings of warmth in the face, neck, and chest, or sudden strong feelings of heat and sweating ("hot flashes") in women during menopause.


This medicine is available only with your doctor's prescription.


Before Using Menostar


In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:


Allergies


Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.


Pediatric


Use of estradiol transdermal spray is not indicated in the pediatric population. Safety and efficacy have not been established.


Geriatric


Although appropriate studies on the relationship of age to the effects of estradiol transdermal spray have not been performed in the geriatric population, no geriatric-specific problems have been documented to date. However, elderly patients are more likely to have breast cancer, stroke, or dementia, which may require caution in patients receiving estradiol transdermal spray.


Pregnancy








Pregnancy CategoryExplanation
All TrimestersXStudies in animals or pregnant women have demonstrated positive evidence of fetal abnormalities. This drug should not be used in women who are or may become pregnant because the risk clearly outweighs any possible benefit.

Breast Feeding


Studies suggest that this medication may alter milk production or composition. If an alternative to this medication is not prescribed, you should monitor the infant for side effects and adequate milk intake.


Interactions with Medicines


Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.


Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.


  • Isotretinoin

  • Theophylline

  • Tizanidine

  • Tranexamic Acid

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.


  • Alprazolam

  • Amoxicillin

  • Ampicillin

  • Amprenavir

  • Aprepitant

  • Atazanavir

  • Bacampicillin

  • Betamethasone

  • Bexarotene

  • Bosentan

  • Carbamazepine

  • Clarithromycin

  • Colesevelam

  • Cyclosporine

  • Darunavir

  • Delavirdine

  • Doxycycline

  • Efavirenz

  • Etravirine

  • Fosamprenavir

  • Fosaprepitant

  • Fosphenytoin

  • Ginseng

  • Griseofulvin

  • Itraconazole

  • Ketoconazole

  • Lamotrigine

  • Levothyroxine

  • Licorice

  • Minocycline

  • Modafinil

  • Mycophenolate Mofetil

  • Mycophenolic Acid

  • Nelfinavir

  • Nevirapine

  • Oxcarbazepine

  • Oxytetracycline

  • Phenobarbital

  • Phenytoin

  • Pioglitazone

  • Prednisolone

  • Primidone

  • Rifabutin

  • Rifampin

  • Rifapentine

  • Ritonavir

  • Rosuvastatin

  • Rufinamide

  • Selegiline

  • St John's Wort

  • Tacrine

  • Telaprevir

  • Tetracycline

  • Tipranavir

  • Topiramate

  • Troglitazone

  • Troleandomycin

  • Voriconazole

  • Warfarin

Interactions with Food/Tobacco/Alcohol


Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.


Using this medicine with any of the following may cause an increased risk of certain side effects but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use this medicine, or give you special instructions about the use of food, alcohol, or tobacco.


  • Caffeine

  • Grapefruit Juice

Other Medical Problems


The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:


  • Abnormal or unusual vaginal bleeding or

  • Blood clots (e.g., deep vein thrombosis, pulmonary embolism), active or history of or

  • Breast cancer, known or suspected, or a history of or

  • Heart attack, active or recent (within the past 12 months) or

  • Liver disease or

  • Stroke, active or recent (within the past 12 months) or

  • Surgery with a long period of inactivity or

  • Tumors (estrogen-dependent), known or suspected—Should not be used in patients with these conditions.

  • Asthma or

  • Cancer, history of or

  • Diabetes or

  • Edema (fluid retention or body swelling) or

  • Endometriosis or

  • Epilepsy (seizures) or

  • Gallbladder disease or

  • Heart disease or

  • Hypercalcemia (high calcium in the blood) or

  • Hypertension (high blood pressure) or

  • Hypertriglyceridemia (high triglycerides or fats in the blood) or

  • Hypocalcemia (low calcium in the blood), severe or

  • Hypothyroidism (an underactive thyroid) or

  • Jaundice during pregnancy or from using hormonal therapy in the past or

  • Liver tumors or

  • Migraine headache or

  • Porphyria (an enzyme problem) or

  • Systemic lupus erythematosus (SLE)—Use with caution. May make these conditions worse.

Proper Use of estradiol

This section provides information on the proper use of a number of products that contain estradiol. It may not be specific to Menostar. Please read with care.


It is very important that you use this medicine only as directed by your doctor. Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered. To do so may cause unwanted side effects.


This medicine is for use on the skin only. Do not get it in your eyes, nose, mouth, breast, or vagina. Do not use it on skin areas that have cuts, scrapes, or burns. If it does get on these areas, rinse it off right away with water.


This medicine comes with a patient information insert. Read and follow the instructions in the insert carefully. Ask your doctor if you have any questions.


Wash your hands with soap and water before and after using this medicine.


To use the spray:


  • The spray form of this medicine comes in an applicator that delivers a measured amount of estradiol to the skin with each spray. When using a new spray applicator, prime the pump by holding the spray upright and pumping 3 times. Priming is only necessary the first time you use a new spray applicator; do not prime again.

  • Apply the medicine to clean, dry, and unbroken skin on the inside of the forearm between the elbow and the wrist. Do not apply the medicine directly to your breasts or in or around the vagina.

  • Allow the medicine to dry for at least 2 minutes before dressing, and at least 1 hour before washing.

  • If your doctor tells you to increase your dose, move the applicator to an area of the skin next to your previous application site, before applying the second or third spray.

  • Do not rub Evamist® spray into your skin.

  • Do not allow your child to touch the area of the arm where the medicine was sprayed. If you cannot avoid being close with your child, wear clothes with long sleeves to cover the application site.

  • If your child comes in direct contact with the arm where the medicine was sprayed, wash your child's skin right away with soap and water.

  • Do not allow your pets to lick or touch the arm where the medicine was sprayed.

  • Always place the protective cover back on the applicator of the spray.

  • Do not use the applicator for more than 75 sprays.

  • Apply sunscreen at least 1 hour before applying Evamist®.

The spray contains alcohol and is flammable. Avoid using it near an open flame or while smoking.


Dosing


The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.


The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.


  • For transdermal dosage form (spray):
    • For hot flashes and other symptoms caused by menopause:
      • Adults—At first, one spray once a day, usually in the morning. Your doctor may adjust your dose as needed.

      • Children—Use is not recommended.



Missed Dose


If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.


Do not use Evamist® spray if it has been more than 12 hours since you missed your last dose.


Storage


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.


Keep out of the reach of children.


Do not keep outdated medicine or medicine no longer needed.


Ask your healthcare professional how you should dispose of any medicine you do not use.


Precautions While Using Menostar


It is very important that your doctor check your progress at regular visits to make sure this medicine is working properly and does not cause unwanted effects. Pelvic exam, breast exam, and mammogram (breast x-ray) may be needed to check for unwanted effects, unless your doctor tells you otherwise.


It is unlikely that a postmenopausal woman may become pregnant. But, you should know that using this medicine while you are pregnant could harm your unborn baby. If you think you have become pregnant while using the medicine, tell your doctor right away.


Using large doses of this medicine over a long period of time may increase your risk of heart attack, stroke, blood clots, dementia, breast cancer, or uterine cancer. Talk with your doctor about this risk. If you still have your uterus (womb), ask your doctor if you should also use a progestin medicine.


Your risk of heart disease or stroke from this medicine is higher if you smoke. Your risk is also increased if you have diabetes or high cholesterol, or if you are overweight. Talk with your doctor about ways to stop smoking. Keep your diabetes under control. Ask your doctor about diet and exercise to control your weight and blood cholesterol level.


Tell the medical doctor or dentist in charge that you are using this medicine before any kind of surgery (including dental surgery) or emergency treatment. Your doctor will decide whether you should continue using this medicine.


This medicine may also increase your risk of certain types of cancer. Talk to your doctor if you have concerns about this risk.


Using this medicine alone may increase your risk of getting cancer of the uterus (womb). Check with your doctor right away if you have unusual vaginal bleeding while you are using this medicine.


Stop using this medicine and check with your doctor immediately if severe headache or sudden loss of vision or any other change in vision occurs while you are using this medicine. Your doctor may want you to have your eyes checked by an ophthalmologist (eye doctor).


Check with your child's doctor right away if your child starts to have the following symptoms: nipple or breast swelling or tenderness in females, or enlargement of the breasts in males. Your child may have been exposed to this medicine.


Do not allow your pets to lick or touch the arm where this medicine was applied. Small pets may be sensitive to this medicine. Call your pet's veterinarian if your pet starts to have the following symptoms: nipple or breast enlargement, swelling of the vulva, or any signs of illness.


Before you have any medical tests, tell the medical doctor in charge that you are taking this medicine. The results of some tests may be affected by this medicine.


Do not take other medicines or drink grapefruit juice unless you discuss it with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal (e.g., St. John's wort) or vitamin supplements.


Menostar Side Effects


Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.


Check with your doctor immediately if any of the following side effects occur:


Incidence not known
  • Abdominal or stomach cramps or pain

  • acid or sour stomach

  • anxiety

  • backache

  • belching

  • blistering, peeling, or loosening of the skin

  • bloating

  • blurred vision

  • breast tenderness, enlargement, pain, or discharge

  • change in vaginal discharge

  • changes in skin color

  • changes in vision

  • chest pain or discomfort

  • chills

  • clay-colored stools

  • clear or bloody discharge from the nipple

  • confusion

  • constipation

  • convulsions

  • cough

  • darkening of the urine

  • diarrhea

  • difficulty with breathing

  • difficulty with swallowing

  • dimpling of the breast skin

  • dizziness or lightheadedness

  • double vision

  • fainting

  • fast heartbeat

  • fever

  • fluid-filled skin blisters

  • full or bloated feeling or pressure in the stomach

  • headache

  • headache, severe and throbbing

  • heartburn

  • hives

  • indigestion

  • inverted nipple

  • irregular heartbeats

  • itching of the skin

  • itching of the vagina or genital area

  • joint or muscle pain

  • large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs

  • light-colored stools

  • loss of appetite

  • loss of bladder control

  • lump in the breast or under the arm

  • migraine headache

  • mood or mental changes

  • muscle cramps in the hands, arms, feet, legs, or face

  • muscle spasm or jerking of all extremities

  • nausea

  • noisy breathing

  • numbness and tingling around the mouth, fingertips, or feet

  • pain during sexual intercourse

  • pain in the ankles or knees

  • pain or discomfort in the arms, jaw, back, or neck

  • pain or feeling of pressure in the pelvis

  • pain, redness, or swelling in the arm, foot, or leg

  • painful, red lumps under the skin, mostly on the legs

  • pains in the stomach, side, or abdomen, possibly radiating to the back

  • persistent crusting or scaling of the nipple

  • poor insight and judgment

  • problems with memory or speech

  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue

  • rash

  • red, irritated eyes

  • redness or swelling of the breast

  • sensitivity to the sun

  • shortness of breath

  • skin thinness

  • sore on the skin of the breast that does not heal

  • sore throat

  • sores, ulcers, or white spots in the mouth or on the lips

  • stomach discomfort, upset, or pain

  • sudden loss of consciousness

  • sudden shortness of breath or troubled breathing

  • sweating

  • swelling

  • swelling of the abdominal or stomach area

  • thick, white vaginal discharge with no odor or with a mild odor

  • tightness in the chest

  • tremor

  • trouble recognizing objects

  • trouble thinking and planning

  • trouble walking

  • unexpected or excess milk flow from the breasts

  • unpleasant breath odor

  • unusual tiredness or weakness

  • unusually heavy or unexpected menstrual bleeding

  • vaginal bleeding or spotting

  • vomiting

  • vomiting of blood

  • wheezing

  • yellow eyes or skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:


Less common
  • Back pain

  • difficulty with moving

  • muscle aches

  • muscle pain or stiffness

  • stuffy or runny nose

Incidence not known
  • Decreased interest in sexual intercourse

  • heavy bleeding

  • hives or welts

  • inability to have or keep an erection

  • increased hair growth, especially on the face

  • increased in sexual ability, desire, drive, or performance

  • increased interest in sexual intercourse

  • irritability

  • leg cramps

  • loss in sexual ability, desire, drive, or performance

  • loss of scalp hair

  • mental depression

  • mood disturbances

  • patchy brown or dark brown discoloration of the skin

  • redness of the skin

  • twitching, uncontrolled movements of the tongue, lips, face, arms, or legs

  • weight changes

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.


Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.



The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.


The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.

Menopause Formula Progesterone


Generic Name: progesterone (proe JESS te rone)

Brand Names: First Progesterone MC10, First Progesterone MC5, Progest, Prometrium


What is Menopause Formula Progesterone (progesterone)?

Progesterone is a female hormone important for the regulation of ovulation and menstruation.


Progesterone is used to cause menstrual periods in women who have not yet reached menopause but are not having periods due to a lack of progesterone in the body. Progesterone is also used to prevent overgrowth in the lining of the uterus in postmenopausal women who are receiving estrogen hormone replacement therapy.


Progesterone should not be used to prevent heart disease or dementia, because this medication may actually increase your risk of developing these conditions.


Progesterone may also be used for other purposes not listed in this medication guide.


What is the most important information I should know about Menopause Formula Progesterone (progesterone)?


Do not use this medication without telling your doctor if you are pregnant. It could cause harm to the unborn baby. Use an effective form of birth control, and tell your doctor if you become pregnant during treatment. Some forms of this medication may contain peanut oil. Do not use progesterone without telling your doctor if you have a peanut allergy.

Using progesterone can increase your risk of blood clots, stroke, heart attack, or breast cancer.


Do not use this medication if you have any of the following conditions: a history of breast cancer, abnormal vaginal bleeding, liver disease, if you are pregnant, or if you have had a stroke, heart attack, or blood clot within the past year.

Progesterone is sometimes given for only a short period of time, such as 6 to 12 days at a time during each menstrual cycle. Following your dosing schedule is very important for this medication to be effective. Try not to miss any doses.


Progesterone may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.

Progesterone should not be used to prevent heart disease or dementia, because this medication may actually increase your risk of developing these conditions.


What should I discuss with my healthcare provider before using Menopause Formula Progesterone (progesterone)?


Some forms of this medication may contain peanut oil. Do not use progesterone without telling your doctor if you have a peanut allergy. Do not use progesterone if you have:

  • a history of breast cancer;




  • abnormal vaginal bleeding that a doctor has not checked;




  • liver disease;




  • if you are pregnant; or




  • if you have had a stroke, heart attack, or blood clot within the past year.



If you have any of these other conditions, you may need a dose adjustment or special tests to safely use progesterone:



  • heart disease, circulation problems;




  • risk factors for coronary artery disease (such as smoking, being overweight, and having high blood pressure or high cholesterol);




  • migraines,




  • asthma;




  • kidney disease;




  • seizures or epilepsy;




  • a history of depression; or




  • diabetes.




Do not use progesterone without your doctor's consent if you are pregnant. Tell your doctor if you become pregnant during treatment. Use an effective form of birth control while you are using this medication. Progesterone can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I use Menopause Formula Progesterone (progesterone)?


Use this medication exactly as it was prescribed for you. Do not use larger amounts, or use it for longer than recommended by your doctor. Follow the directions on your prescription label.


Progesterone is sometimes given for only a short period of time, such as 6 to 12 days at a time during each menstrual cycle. Following your dosing schedule is very important for this medication to be effective. Try not to miss any doses.


This medication comes with patient instructions for safe and effective use. Follow these directions carefully. Ask your doctor or pharmacist if you have any questions.


Take the pill form of progesterone with a full glass of water.

Apply progesterone cream to the skin as directed by your doctor.


Progesterone injection is given as a shot into a muscle. Your doctor, nurse, or other healthcare provider will give you this injection. You may be given instructions on how to use your injections at home. Do not use this medicine at home if you do not fully understand how to give the injection and properly dispose of needles and syringes used in giving the medicine.


This medication can cause you to have unusual results with certain medical tests. Tell any doctor who treats you that you are using progesterone.


Your doctor will need to see you on a regular basis while you are using this medication. Do not miss any scheduled appointments.


Store progesterone at room temperature away from moisture, heat, and light.

What happens if I miss a dose?


Use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.


Call your doctor if you miss more than one dose of this medication.

What happens if I overdose?


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while using Menopause Formula Progesterone (progesterone)?


Progesterone may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.

Menopause Formula Progesterone (progesterone) side effects


Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using this medication and call your doctor at once if you have any of these serious side effects:

  • sudden numbness or weakness, especially on one side of the body;




  • sudden headache, confusion, pain behind the eyes, problems with vision, speech, or balance;




  • fast or pounding heartbeats;




  • chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling;




  • unusual or unexpected vaginal bleeding;




  • migraine headache;




  • nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);




  • swelling in your hands, ankles, or feet;




  • fever, chills, body aches, flu symptoms;




  • a breast lump; or




  • symptoms of depression (sleep problems, weakness, mood changes).



Less serious side effects may include:



  • mild nausea, diarrhea, bloating, stomach cramps;




  • dizziness, spinning sensation;




  • hot flashes;




  • mild headache;




  • joint pain;




  • breast pain or tenderness;




  • cough;




  • acne or increased hair growth;




  • changes in weight; or




  • vaginal itching, dryness, or discharge.



This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


What other drugs will affect Menopause Formula Progesterone (progesterone)?


There may be other drugs that can interact with progesterone. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.



More Menopause Formula Progesterone resources


  • Menopause Formula Progesterone Side Effects (in more detail)
  • Menopause Formula Progesterone Use in Pregnancy & Breastfeeding
  • Menopause Formula Progesterone Drug Interactions
  • 0 Reviews for Menopause Formula Progesterone - Add your own review/rating


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  • Amenorrhea
  • Endometrial Hyperplasia, Prophylaxis
  • Perimenopausal Symptoms
  • Premature Labor
  • Progesterone Insufficiency
  • Seizures
  • Uterine Bleeding


Where can I get more information?


  • Your pharmacist can provide more information about progesterone.

See also: Menopause Formula Progesterone side effects (in more detail)


Menthol Spray


Pronunciation: MEN-thol
Generic Name: Menthol
Brand Name: Examples include Berri-Freez and Stopain


Menthol Spray is used for:

Relieving minor pain caused by conditions such as arthritis, bursitis, tendonitis, muscle strains or sprains, backache, bruising, and cramping. It may also be used for other conditions as determined by your doctor.


Menthol Spray is a topical analgesic. It works by temporarily relieving minor pain.


Do NOT use Menthol Spray if:


  • you are allergic to any ingredient in Menthol Spray

Contact your doctor or health care provider right away if any of these apply to you.



Before using Menthol Spray:


Some medical conditions may interact with Menthol Spray. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:


  • if you are pregnant, planning to become pregnant, or are breast-feeding

  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

  • if you have allergies to medicines, foods, or other substances

  • if you have cut, scraped, irritated, or damaged skin at the application site

Some MEDICINES MAY INTERACT with Menthol Spray. However, no specific interactions with Menthol Spray are known at this time.


Ask your health care provider if Menthol Spray may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.


How to use Menthol Spray:


Use Menthol Spray as directed by your doctor. Check the label on the medicine for exact dosing instructions.


  • Wash your hands before and right after using Menthol Spray.

  • Spray Menthol Spray directly onto the affected area. Do not rub or massage the medicine into the skin.

  • Do not wrap, bandage, or use a heating pad on the treated area.

  • Do not apply Menthol Spray more than 4 times daily.

  • If you miss a dose of Menthol Spray, use it as soon as you remember. Continue to use it as directed by your doctor or on the package label.

Ask your health care provider any questions you may have about how to use Menthol Spray.



Important safety information:


  • Menthol Spray is for external use only. Do not get it in your eyes, on your lips, or in your nose, mouth, or genital area. If you get it in any of these areas, rinse right away with cool tap water.

  • If you use topical products too often, your condition may become worse.

  • Do NOT use more than the recommended dose or use for longer than 1 week without checking with your doctor.

  • If your symptoms do not improve within 7 days, if they get worse, or if they clear up and then come back again, contact your doctor.

  • Menthol Spray is flammable. Do not store or use near an open flame or while smoking.

  • Menthol Spray should not be used in CHILDREN younger than 12 years old without first checking with the child's doctor; safety and effectiveness in these children have not been confirmed.

  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Menthol Spray while you are pregnant. It is not known if Menthol Spray is found in breast milk. If you are or will be breast-feeding while you use Menthol Spray, check with your doctor. Discuss any possible risks to your baby.


Possible side effects of Menthol Spray:


All medicines may cause side effects, but many people have no, or minor, side effects. No COMMON side effects have been reported with Menthol Spray. Seek medical attention right away if any of these SEVERE side effects occur:



Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); redness or irritation at the application site.



This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.



If OVERDOSE is suspected:


Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center ( http://www.aapcc.org), or emergency room immediately. Menthol Spray may be harmful if swallowed.


Proper storage of Menthol Spray:

Store Menthol Spray at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat and direct sunlight. Keep Menthol Spray out of the reach of children and away from pets.


General information:


  • If you have any questions about Menthol Spray, please talk with your doctor, pharmacist, or other health care provider.

  • Menthol Spray is to be used only by the patient for whom it is prescribed. Do not share it with other people.

  • If your symptoms do not improve or if they become worse, check with your doctor.

  • Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Menthol Spray. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.



Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

Mentax Cream


Pronunciation: byoo-TEN-a-feen
Generic Name: Butenafine
Brand Name: Mentax


Mentax Cream is used for:

Treating certain fungal infections of the skin. It may also be used to treat other conditions as determined by your doctor, which may not be listed in the professional package insert.


Mentax Cream is a topical antifungal. It works by killing sensitive fungi by interfering with the formation of the fungal cell membrane and weakening it.


Do NOT use Mentax Cream if:


  • you are allergic to any ingredient in Mentax Cream

Contact your doctor or health care provider right away if any of these apply to you.



Before using Mentax Cream:


Some medical conditions may interact with Mentax Cream. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:


  • if you are pregnant, planning to become pregnant, or are breast-feeding

  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

  • if you have allergies to medicines, foods, or other substances

Some MEDICINES MAY INTERACT with Mentax Cream. However, no specific interactions with Mentax Cream are known at this time.


This may not be a complete list of all interactions that may occur. Ask your health care provider if Mentax Cream may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.


How to use Mentax Cream:


Use Mentax Cream as directed by your doctor. Check the label on the medicine for exact dosing instructions.


  • Mentax Cream works best if it is used at the same time(s) each day.

  • Wash and completely dry the affected area. Gently rub the medicine in until it is evenly distributed.

  • Use enough cream to cover the affected areas and the healthy skin close to the affected areas.

  • Wash your hands immediately after using Mentax Cream.

  • Do not cover the area with bandages or other dressings unless directed by your health care provider.

  • Continue to use Mentax Cream for the full treatment time recommended by your health care provider, even though symptoms have gotten better.

  • If you miss a dose of Mentax Cream, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Mentax Cream.



Important safety information:


  • Do not use Mentax Cream for other skin conditions at a later time.

  • Mentax Cream is for external use only. Avoid contact with nose, mouth, and eyes. If you get Mentax Cream in your eyes, immediately rinse out with cool tap water.

  • Mentax Cream is not for use in CHILDREN younger than 12 years of age. Safety and effectiveness in this age group have not been confirmed.

  • PREGNANCY and BREAST-FEEDING: If you are pregnant or plan on becoming pregnant, discuss with your doctor the benefits and risks of using Mentax Cream during pregnancy. It is unknown if Mentax Cream is excreted in breast milk. If you are or will be breast-feeding, check with your doctor to discuss the benefits and risks to your baby.


Possible side effects of Mentax Cream:


All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:



Burning; inflammation; irritation; itching; redness; stinging.



Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue).



This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.


See also: Mentax side effects (in more detail)


If OVERDOSE is suspected:


Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Mentax Cream may be harmful if swallowed.


Proper storage of Mentax Cream:

Store Mentax Cream at room temperature between 59 and 86 degrees F (15 and 30 degrees C) in a tightly-closed container, away from heat, moisture, and light. Do not store in the bathroom. Keep Mentax Cream out of the reach of children and away from pets.


General information:


  • If you have any questions about Mentax Cream, please talk with your doctor, pharmacist, or other health care provider.

  • Mentax Cream is to be used only by the patient for whom it is prescribed. Do not share it with other people.

  • If your symptoms do not improve or if they become worse, check with your doctor.

  • Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Mentax Cream. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.



Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Mentax resources


  • Mentax Side Effects (in more detail)
  • Mentax Use in Pregnancy & Breastfeeding
  • Mentax Support Group
  • 0 Reviews for Mentax - Add your own review/rating


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  • Tinea Corporis
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Members Mark Cetirizine





Dosage Form: tablet
Sam's West, Inc. Cetirizine Hydrochloride Tablets, 10 mg Drug Facts

Active ingredient (in each tablet)


Cetirizine HCl 10 mg



Purpose


Antihistamine



Uses


temporarily relieves these symptoms due to hay fever or other upper respiratory allergies:


  • runny nose

  • sneezing

  • itchy, watery eyes

  • itching of the nose or throat


Warnings



Do not use


if you have ever had an allergic reaction to this product or any of its ingredients or to an antihistamine containing hydroxyzine.



Ask a doctor before use if you have


liver or kidney disease. Your doctor should determine if you need a different dose.



Ask a doctor or pharmacist before use if you are


taking tranquilizers or sedatives.



When using this product


  • drowsiness may occur

  • avoid alcoholic drinks

  • alcohol, sedatives, and tranquilizers may increase drowsiness

  • be careful when driving a motor vehicle or operating machinery


Stop use and ask a doctor if


an allergic reaction to this product occurs. Seek medical help right away.



If pregnant or breast-feeding:


  • if breast-feeding: not recommended

  • if pregnant: ask a health professional before use.


Keep out of reach of children.


In case of overdose, get medical help or contact a Poison Control Center right away.



Directions












adults and children


6 years and over
one 10 mg tablet once daily; do not take more than one 10 mg tablet in 24 hours. A 5 mg product may be appropriate for less severe symptoms.
adults 65 years and overask a doctor
children under 6 years of ageask a doctor
consumers with liver or kidney diseaseask a doctor

Other information


  • do not use if printed foil under cap is broken or missing

  • store between 20° to 25°C (68° to 77°F)


Inactive ingredients


corn starch, FD&C blue no. 1, hypromellose, lactose, magnesium stearate, polydextrose, polyethylene glycol, povidone, titanium dioxide, triacetin



Questions or comments?


1-800-809-0469



Principal Display Panel


Original Prescription Strength


Cetirizine


Hydrochloride Tablets, 10 mg/Antihistamine


Allergy


Compare to Zyrtec® active ingredient


24 Hour Relief of: Sneezing; Runny Nose; Itchy, Watery Eyes; Itchy Throat or Nose


Indoor & Outdoor Allergies


Actual Size


Cetirizine Hydrochloride Tablets, 10 mg Stretch Pack










Members Mark Cetirizine 
cetirizine hydrochloride  tablet










Product Information
Product TypeHUMAN OTC DRUGNDC Product Code (Source)68196-458
Route of AdministrationORALDEA Schedule    








Active Ingredient/Active Moiety
Ingredient NameBasis of StrengthStrength
CETIRIZINE HYDROCHLORIDE (CETIRIZINE)CETIRIZINE HYDROCHLORIDE10 mg





Inactive Ingredients
Ingredient NameStrength
No Inactive Ingredients Found


















Product Characteristics
ColorWHITEScoreno score
ShapeOVALSize10mm
FlavorImprint Code4H2
Contains      














Packaging
#NDCPackage DescriptionMultilevel Packaging
168196-458-031 BOTTLE In 1 PACKAGEcontains a BOTTLE
1350 TABLET In 1 BOTTLEThis package is contained within the PACKAGE (68196-458-03)










Marketing Information
Marketing CategoryApplication Number or Monograph CitationMarketing Start DateMarketing End Date
ANDAANDA07833603/24/2008


Labeler - Sam's West Inc (051957769)
Revised: 05/2009Sam's West Inc




More Members Mark Cetirizine resources


  • Members Mark Cetirizine Side Effects (in more detail)
  • Members Mark Cetirizine Dosage
  • Members Mark Cetirizine Use in Pregnancy & Breastfeeding
  • Drug Images
  • Members Mark Cetirizine Drug Interactions
  • Members Mark Cetirizine Support Group
  • 73 Reviews for Members Mark Cetirizine - Add your own review/rating


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